CAMP

Across TCGA patient cohorts, CAMP mutation is significantly associated with the RNA expression of many other genes, with 79 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAMP-associated genes across cancer lineages are RNU6-263P, RNASE11, and RNA5SP71. Each is linked with CAMP in more than 1 cancer types. Because this analysis shows association rather than direction, both CAMP-to-partner and partner-to-CAMP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-263P grouped by CAMP-low versus CAMP-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAMP→partner) and Y-score (partner→CAMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-263P →	+0.648	+5.790	<.001	.003	3	2
SKCM	RNASE11 →	+0.024	+7.816	<.001	.008	3	2
COAD	RNA5SP71 →	+0.898	+5.693	.008	.003	3	1
COAD	RNA5SP431 →	+0.948	+6.251	.004	.001	3	1
COAD	RPL26P34 →	+0.365	+5.017	<.001	.009	3	1
COAD	RPL32P19 →	+0.287	+5.017	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 79 associations by consensus.

RNU6-263P by CAMP expression — COAD

Explore this box plot interactively →