CAMLG

Across TCGA pan-cancer cohorts, CAMLG mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated CAMLG data layer compared with 24 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher CAMLG mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CAMLG expression acts as an unfavorable survival marker, although some lineages such as GBM and PDAC show a favorable association.

LSCC, CCRCC, and GBM are the cancer types where CAMLG mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Quartile	III,IV	0.376	0.925	.005	27	view →
CCRCC	DFS	Quartile	III,IV	0.240	0.871	<.001	27	view →
GBM	DFS	Tertile	All	0.514	0.244	.002	18	view →
LUAD	DFS	Median	III,IV	0.409	0.941	.010	5	view →
HNSC	OS	Median	IV	0.721	0.920	.045	2	view →
PDAC	OS	Quartile	III,IV	0.827	0.427	.030	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

CAMLG–LSCC (OS)

Open the LSCC breakdown →