CAMLG

Across TCGA pan-cancer cohorts, CAMLG RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of CAMLG’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CAMLG RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CAMLG is over-expressed in tumor, although a few such as UCEC and BLCA show the opposite, repressed pattern.

KIRC, LIHC, and UCEC are the cancer types where CAMLG tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CAMLG RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	IV	+0.995	<.001	12	view →
LIHC	Male	II,III,IV	+1.035	<.001	9	view →
UCEC	All	All	−1.125	<.001	8	view →
BLCA	All	All	−0.416	.009	7	view →
THCA	All	II,III,IV	+0.254	.002	4	view →
CHOL	All	All	+1.882	<.001	3	view →
KICH	Female	All	−1.041	<.001	3	view →
COAD	All	II,III,IV	+0.317	.006	3	view →
LUSC	All	All	−0.190	.014	3	view →
BRCA	Female	All	−0.140	.038	2	view →
LUAD	Female	III,IV	−0.442	.009	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

CAMLG–KIRC

Open the KIRC breakdown →