CAMLG

Across TCGA patient cohorts, CAMLG mutation is significantly associated with the RNA expression of many other genes, with 225 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAMLG-associated genes across cancer lineages are LINC01066, RPL7AP61, and MIR4460. Each is linked with CAMLG in more than 1 cancer types. Because this analysis shows association rather than direction, both CAMLG-to-partner and partner-to-CAMLG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01066 grouped by CAMLG-low versus CAMLG-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAMLG→partner) and Y-score (partner→CAMLG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LINC01066 →	+0.275	+6.409	<.001	<.001	3	2
COAD	RPL7AP61 →	+0.097	+6.142	.001	<.001	3	2
BLCA	MIR4460 →	+0.413	+4.926	.004	.002	3	2
UCEC	OR2E1P →	+0.104	+3.442	<.001	.004	3	2
UCEC	RNU6-927P →	+0.323	+3.242	<.001	.001	3	2
LUAD	RNU6-710P →	+0.288	+5.327	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 225 associations by consensus.

LINC01066 by CAMLG expression — COAD

Explore this box plot interactively →