CAMKV

Across TCGA cell cohorts, CAMKV mutation is significantly associated with the RNA expression of many other genes, with 69 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CAMKV-associated genes across cancer lineages are TP53AIP1, AQP12B, and GPRIN2. Each is linked with CAMKV in more than 1 cancer types. Because this analysis shows association rather than direction, both CAMKV-to-partner and partner-to-CAMKV results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TP53AIP1 grouped by CAMKV-low versus CAMKV-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAMKV→partner) and Y-score (partner→CAMKV) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TP53AIP1 →	+0.084	+3.554	<.001	.007	3	2
BLOOD_Leukemia	AQP12B →	+0.198	+3.926	<.001	.003	3	2
BLOOD_Leukemia	GPRIN2 →	+0.039	+4.004	<.001	.002	3	2
LARGE_INTESTINE	SH3GL2 →	+1.656	+3.252	<.001	.009	3	1
LARGE_INTESTINE	POM121L2 →	+0.107	+3.761	<.001	.001	3	1
LARGE_INTESTINE	SPANXN3 →	+0.109	+3.237	.003	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 69 associations by consensus.

TP53AIP1 by CAMKV expression — BLOOD_Leukemia

Explore this box plot interactively →