CAMK2N1

Across TCGA pan-cancer cohorts, CAMK2N1 mass-spec protein differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of CAMK2N1’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where CAMK2N1 mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types CAMK2N1 is over-expressed in tumor, although a few such as LSCC and LUAD show the opposite, repressed pattern.

LSCC, LUAD, and CCRCC are the cancer types where CAMK2N1 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CAMK2N1 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LSCC	Male	All	−1.366	<.001	8	view →
LUAD	Female	II,III,IV	−1.047	<.001	8	view →
CCRCC	Male	All	+0.466	.005	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

CAMK2N1–LSCC

Open the LSCC breakdown →