CAMK2D

Across TCGA pan-cancer cohorts, CAMK2D mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated CAMK2D data layer compared with 25 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher CAMK2D mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated CAMK2D expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCEC show a favorable association.

HNSC, LSCC, and PDAC are the cancer types where CAMK2D mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	IV	0.896	0.786	.016	11	view →
LSCC	DFS	Quartile	II,III,IV	0.519	1.000	.006	11	view →
PDAC	DFS	Median	IV	0.214	0.785	.006	9	view →
UCEC	DFS	Quartile	All	0.961	0.749	.022	4	view →
LUAD	OS	Quartile	II,III,IV	0.721	0.307	.020	2	view →
GBM	OS	Median	All	0.669	0.422	.007	2	view →
CCRCC	DFS	Median	II,III,IV	0.720	0.506	.047	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

CAMK2D–HNSC (OS)

Open the HNSC breakdown →