CAMK2D

Across TCGA pan-cancer cohorts, CAMK2D RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of CAMK2D’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where CAMK2D RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CAMK2D is over-expressed in tumor, although a few such as COAD and UCEC show the opposite, repressed pattern.

HNSC, COAD, and KIRC are the cancer types where CAMK2D tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CAMK2D RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Female	All	+0.916	<.001	10	view →
COAD	Female	All	−1.023	<.001	9	view →
KIRC	All	All	+0.434	<.001	8	view →
UCEC	All	All	−1.000	<.001	6	view →
BLCA	All	III,IV	−0.726	.008	6	view →
BRCA	Female	All	−0.551	<.001	6	view →
READ	Female	All	−1.330	<.001	5	view →
CHOL	All	All	+0.951	<.001	3	view →
KIRP	All	All	+0.519	.002	2	view →
PRAD	All	All	−0.477	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

CAMK2D–HNSC

Open the HNSC breakdown →