CAMK2D

Across TCGA patient cohorts, CAMK2D mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAMK2D-associated genes across cancer lineages are S6_pS240_S244, ASNS, and 14-3-3_beta. Each is linked with CAMK2D in more than 1 cancer types. Because this analysis shows association rather than direction, both CAMK2D-to-partner and partner-to-CAMK2D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, S6_pS240_S244 grouped by CAMK2D-low versus CAMK2D-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAMK2D→partner) and Y-score (partner→CAMK2D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	S6_pS240_S244 →	+0.380	+2.000	.012	.030	3	2
UCEC	ASNS →	+0.405	+2.115	.002	.017	3	2
UCEC	14-3-3_beta →	-0.093	-2.432	.013	.018	3	1
UCEC	A-Raf_pS299 →	-0.124	-2.584	.005	.010	3	1
UCEC	ERK2 →	+0.222	+2.459	.002	.018	3	1
UCEC	Heregulin →	-0.136	-2.115	.003	.017	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

S6_pS240_S244 by CAMK2D expression — UCEC

Explore this box plot interactively →