CAMK2A

Across TCGA patient cohorts, CAMK2A protein abundance is significantly associated with the RNA expression of many other genes, with 4,612 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CAMK2A-associated genes across cancer lineages are CAMK4, HSPB3, and GRID1. Each is linked with CAMK2A in more than 2 cancer types. Because this analysis shows association rather than direction, both CAMK2A-to-partner and partner-to-CAMK2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAMK2A versus CAMK4 in HNSC, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAMK2A→partner) and Y-score (partner→CAMK2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CAMK4 →	+0.513	+0.831	.002	.004	3	3
HNSC	HSPB3 →	+1.401	+0.987	<.001	<.001	3	3
GBM	GRID1 →	+0.770	+0.643	<.001	.002	3	3
GBM	DYNC1I1 →	+1.003	+0.759	<.001	<.001	3	3
GBM	NEFH →	+0.814	+0.680	<.001	<.001	3	2
GBM	PVALB →	+0.688	+0.557	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,612 associations by consensus.

CAMK2A vs CAMK4 — HNSC

Explore this scatter interactively →