CAMK2A

Across TCGA cell cohorts, CAMK2A RNA expression is significantly associated with the go_rna of many other GO terms, with 1,441 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible CAMK2A-associated GO terms across cancer lineages are Regulation of proteasomal protein catabolic process, CD8-positive, alpha-beta T cell homeostasis, and Negative regulation of amino acid biosynthetic process. Each is linked with CAMK2A in more than 8 cancer types. Because this analysis shows association rather than direction, both CAMK2A-to-partner and partner-to-CAMK2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of proteasomal protein catabolic process grouped by CAMK2A-low versus CAMK2A-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CAMK2A→partner) and Y-score (partner→CAMK2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of proteasomal protein catabolic process →	+0.057	+0.075	<.001	.001	2	9
UPPER_AERODIGESTIVE_TRACT	CD8-positive, alpha-beta T cell homeostasis →	+0.119	+0.905	<.001	.001	3	7
UPPER_AERODIGESTIVE_TRACT	Negative regulation of amino acid biosynthetic process →	+0.240	+1.020	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Negative regulation of amino acid metabolic process →	+0.240	+1.020	<.001	<.001	3	7
BONE	Negative regulation of cell adhesion →	+0.074	+0.360	.001	.009	3	7
LARGE_INTESTINE	Regulation of protein localization to nucleus →	+0.043	+0.050	.009	.003	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,441 associations by consensus.

Regulation of proteasomal protein catabolic process by CAMK2A expression — OVARY

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