CALN1

Across TCGA cell cohorts, CALN1 mutation is significantly associated with the RNA expression of many other genes, with 75 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CALN1-associated genes across cancer lineages are ADAD1, FAM162B, and OR13C8. Each is linked with CALN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CALN1-to-partner and partner-to-CALN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADAD1 grouped by CALN1-low versus CALN1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CALN1→partner) and Y-score (partner→CALN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	ADAD1 →	+0.050	+4.786	<.001	<.001	3	1
LUNG_NSCLC_LUAD	FAM162B →	+0.199	+4.050	<.001	.004	3	1
LUNG_NSCLC_LUAD	OR13C8 →	+0.021	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	CLEC20A →	+0.036	+3.866	<.001	.006	3	1
OVARY	OR2AK2 →	+0.060	+4.029	<.001	.009	3	1
LARGE_INTESTINE	CRACD →	+0.973	+3.212	.007	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 75 associations by consensus.

ADAD1 by CALN1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →