CALML5

Across TCGA cell cohorts, CALML5 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CALML5-associated genes across cancer lineages are MSGN1, LMNTD1, and TAFA1. Each is linked with CALML5 in more than 1 cancer types. Because this analysis shows association rather than direction, both CALML5-to-partner and partner-to-CALML5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MSGN1 grouped by CALML5-low versus CALML5-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CALML5→partner) and Y-score (partner→CALML5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MSGN1 →	+0.082	+3.345	<.001	.007	3	1
LARGE_INTESTINE	LMNTD1 →	+0.118	+3.554	.005	.007	3	1
LARGE_INTESTINE	TAFA1 →	+0.276	+5.009	<.001	<.001	3	1
LARGE_INTESTINE	C14orf180 →	+0.176	+3.155	<.001	.008	3	1
LARGE_INTESTINE	ANKRD63 →	+0.337	+3.700	<.001	.004	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

MSGN1 by CALML5 expression — LARGE_INTESTINE

Explore this box plot interactively →