CALM2

Across TCGA cell cohorts, CALM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,559 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CALM2-associated GO terms across cancer lineages are Negative regulation of ubiquitin protein ligase activity, GDP-L-fucose biosynthetic process, and Regulation of mitotic spindle checkpoint. Each is linked with CALM2 in more than 10 cancer types. Because this analysis shows association rather than direction, both CALM2-to-partner and partner-to-CALM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of ubiquitin protein ligase activity grouped by CALM2-low versus CALM2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CALM2→partner) and Y-score (partner→CALM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Negative regulation of ubiquitin protein ligase activity →	+0.175	+0.621	<.001	<.001	3	11
STOMACH	GDP-L-fucose biosynthetic process →	-0.088	-0.562	.004	.003	3	10
BLOOD_Leukemia	Regulation of mitotic spindle checkpoint →	+0.102	+0.763	<.001	<.001	3	10
BLOOD_Leukemia	Chromosome localization →	+0.089	+0.813	<.001	<.001	2	11
URINARY_TRACT	Regulation of chromosome separation →	+0.113	+0.553	<.001	.003	2	11
BLOOD_Lymphoma	Regulation of sister chromatid segregation →	+0.110	+1.033	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,559 associations by consensus.

Negative regulation of ubiquitin protein ligase activity by CALM2 expression — URINARY_TRACT

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