CALHM6-AS1

Across TCGA pan-cancer cohorts, CALHM6-AS1 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated CALHM6-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher CALHM6-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CALHM6-AS1 expression acts as an unfavorable survival marker, although some lineages such as SKCM and COAD show a favorable association.

KIRC, SKCM, and TGCT are the cancer types where CALHM6-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.528	0.697	<.001	140	view →
SKCM	OS	Tertile	III,IV	0.709	0.317	<.001	96	view →
TGCT	OS	Tertile	III,IV	0.003	1.000	<.001	78	view →
UVM	OS	Tertile	II,III,IV	0.218	0.718	.006	72	view →
KIRP	DFS	Tertile	All	0.667	0.873	.039	36	view →
DLBC	DFS	Quartile	III,IV	0.074	0.984	.008	25	view →
MESO	OS	Median	All	0.310	0.461	.014	24	view →
COAD	OS	Tertile	III,IV	1.000	0.514	.032	18	view →
READ	DFS	Tertile	All	0.111	0.799	.001	18	view →
STAD	DFS	Quartile	III,IV	0.235	0.547	.001	15	view →
LUAD	DFS	Quartile	IV	0.200	0.618	.028	12	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

CALHM6-AS1–KIRC (OS)

Open the KIRC breakdown →