CALHM3

Across TCGA patient cohorts, CALHM3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,928 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible CALHM3-associated GO terms across cancer lineages are Positive regulation of cell growth, Nucleoside monophosphate metabolic process, and Organelle inheritance. Each is linked with CALHM3 in more than 12 cancer types. Because this analysis shows association rather than direction, both CALHM3-to-partner and partner-to-CALHM3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell growth grouped by CALHM3-low versus CALHM3-high in GBM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CALHM3→partner) and Y-score (partner→CALHM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	Positive regulation of cell growth →	+0.020	+0.087	<.001	<.001	3	13
PAAD	Nucleoside monophosphate metabolic process →	+0.025	+1.390	<.001	.002	3	11
UVM	Organelle inheritance →	+0.057	+0.024	<.001	<.001	3	11
UCEC	Amyloid precursor protein metabolic process →	+0.025	+0.518	<.001	<.001	3	11
UVM	Regulation of protein localization to chromatin →	+0.060	+0.041	<.001	.005	3	11
UCEC	Negative regulation of kinase activity →	+0.016	+0.380	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,928 associations by consensus.

Positive regulation of cell growth by CALHM3 expression — GBM

Explore this box plot interactively →