CALCRL

Across TCGA patient cohorts, CALCRL protein abundance is significantly associated with the RNA expression of many other genes, with 14,617 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CALCRL-associated genes across cancer lineages are GAPDHP59, TAL1, and ZNF385D. Each is linked with CALCRL in more than 5 cancer types. Because this analysis shows association rather than direction, both CALCRL-to-partner and partner-to-CALCRL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CALCRL versus GAPDHP59 in GBM, with a Pearson correlation of 0.77.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CALCRL→partner) and Y-score (partner→CALCRL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GAPDHP59 →	+1.311	+1.061	<.001	<.001	3	6
CCRCC	TAL1 →	+1.106	+0.671	<.001	<.001	3	6
BRCA	ZNF385D →	+0.804	+0.357	.002	.001	3	5
CCRCC	EMCN →	+1.515	+0.597	<.001	<.001	3	5
CCRCC	CD34 →	+0.819	+0.543	<.001	<.001	3	5
UCEC	ADAMTS9-AS1 →	+0.652	+0.344	.008	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,617 associations by consensus.

CALCRL vs GAPDHP59 — GBM

Explore this scatter interactively →