CALCRL

Across TCGA patient cohorts, CALCRL protein abundance is significantly associated with the protein abundance of many other proteins, with 28,194 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CALCRL-associated proteins across cancer lineages are PECAM1, RASIP1, and EIF3F_S258. Each is linked with CALCRL in more than 6 cancer types. Because this analysis shows association rather than direction, both CALCRL-to-partner and partner-to-CALCRL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CALCRL versus PECAM1 in CCRCC, with a Pearson correlation of 0.76.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CALCRL→partner) and Y-score (partner→CALCRL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PECAM1 →	+0.488	+0.660	<.001	<.001	3	7
CCRCC	RASIP1 →	+0.651	+0.794	<.001	<.001	3	7
BRCA	EIF3F_S258 →	-0.660	-0.343	.001	.001	3	6
LUAD	PALD1 →	+0.347	+0.428	<.001	<.001	3	6
BRCA	TNS2_S931 →	+0.868	+0.360	.001	<.001	3	6
CCRCC	PLVAP →	+0.904	+0.764	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 28,194 associations by consensus.

CALCRL vs PECAM1 — CCRCC

Explore this scatter interactively →