CALCOCO1

Across TCGA patient cohorts, CALCOCO1 mutation is significantly associated with the RNA expression of many other genes, with 2,292 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CALCOCO1-associated genes across cancer lineages are TRAJ46, RNA5SP60, and FAM207CP. Each is linked with CALCOCO1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CALCOCO1-to-partner and partner-to-CALCOCO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAJ46 grouped by CALCOCO1-low versus CALCOCO1-high in OV.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CALCOCO1→partner) and Y-score (partner→CALCOCO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TRAJ46 →	+0.546	+5.379	<.001	.001	3	2
OV	RNA5SP60 →	+0.307	+4.676	<.001	.007	3	2
OV	FAM207CP →	+0.081	+4.374	<.001	.006	3	2
SKCM	MIR16-2 →	+0.116	+4.163	<.001	.006	3	2
SKCM	RNY4P17 →	+0.419	+2.913	<.001	<.001	3	2
UCEC	RPS29P32 →	+0.370	+1.955	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,292 associations by consensus.

TRAJ46 by CALCOCO1 expression — OV

Explore this box plot interactively →