CALB2

Across TCGA pan-cancer cohorts, CALB2 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated CALB2 data layer compared with 6 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher CALB2 RNA is associated with better overall survival. In most high-consensus cancer types, elevated CALB2 expression acts as an unfavorable survival marker, although some lineages such as ACC and MESO show a favorable association.

ACC, MESO, and KIRC are the cancer types where CALB2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Median	II,III,IV	0.751	0.405	<.001	119	view →
MESO	OS	Median	All	0.678	0.405	<.001	117	view →
KIRC	DFS	Quartile	All	0.687	0.864	<.001	116	view →
BLCA	DFS	Tertile	IV	0.254	0.696	.001	48	view →
UCEC	OS	Tertile	All	0.892	0.954	.001	44	view →
PAAD	DFS	Median	All	0.189	0.394	.001	32	view →
OV	DFS	Tertile	All	0.473	0.599	.004	30	view →
SCLC	DFS	Median	IV	0.137	0.559	.008	29	view →
COAD	DFS	Quartile	All	0.256	0.814	.001	22	view →
STAD	OS	Quartile	All	0.636	0.771	.017	19	view →
LUSC	DFS	Quartile	III,IV	0.199	0.464	.015	18	view →
KIRP	OS	Median	All	0.581	0.903	.016	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

CALB2–ACC (OS)

Open the ACC breakdown →