CADPS

Across TCGA patient cohorts, CADPS mutation is significantly associated with the RNA expression of many other genes, with 5,701 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CADPS-associated genes across cancer lineages are MIR3908, OIP5, and NPRL2. Each is linked with CADPS in more than 3 cancer types. Because this analysis shows association rather than direction, both CADPS-to-partner and partner-to-CADPS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3908 grouped by CADPS-low versus CADPS-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CADPS→partner) and Y-score (partner→CADPS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR3908 →	+0.179	+2.952	<.001	.003	3	4
UCEC	OIP5 →	+0.699	+1.857	<.001	<.001	3	4
UCEC	NPRL2 →	+0.236	+1.872	<.001	<.001	3	4
LUAD	CIDECP1 →	+0.435	+3.506	<.001	.002	3	4
UCEC	MZT1 →	+0.383	+1.158	.004	.001	3	4
SKCM	NHLRC1 →	-0.696	-1.511	.003	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,701 associations by consensus.

MIR3908 by CADPS expression — CESC

Explore this box plot interactively →