CADM4

Across TCGA patient cohorts, CADM4 protein abundance is significantly associated with the RNA expression of many other genes, with 11,152 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CADM4-associated genes across cancer lineages are ITGA4, MSI1, and CASP4. Each is linked with CADM4 in more than 3 cancer types. Because this analysis shows association rather than direction, both CADM4-to-partner and partner-to-CADM4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CADM4 versus ITGA4 in UCEC, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CADM4→partner) and Y-score (partner→CADM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ITGA4 →	-0.755	-0.377	<.001	.002	3	4
LSCC	MSI1 →	+1.134	+0.485	<.001	<.001	3	4
UCEC	CASP4 →	-0.596	-0.371	<.001	.001	3	4
GBM	BIRC3 →	-1.175	-0.442	<.001	<.001	3	4
GBM	PLXNB1 →	+0.699	+0.441	<.001	<.001	3	4
BRCA	WNK2 →	+1.021	+0.407	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,152 associations by consensus.

CADM4 vs ITGA4 — UCEC

Explore this scatter interactively →