CAD

Across TCGA patient cohorts, CAD RNA expression is significantly associated with the protein abundance of many other proteins, with 20,009 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CAD-associated proteins across cancer lineages are WDR75, CPSF3, and NOL10. Each is linked with CAD in more than 8 cancer types. Because this analysis shows association rather than direction, both CAD-to-partner and partner-to-CAD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAD versus WDR75 in LSCC, with a Pearson correlation of 0.70.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CAD→partner) and Y-score (partner→CAD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	WDR75 →	+0.401	+0.897	<.001	<.001	3	9
BRCA	CPSF3 →	+0.240	+0.564	<.001	<.001	3	8
LSCC	NOL10 →	+0.437	+0.827	<.001	<.001	3	8
LSCC	PDCD11 →	+0.406	+0.718	<.001	<.001	3	8
GBM	SF3B3 →	+0.216	+0.486	<.001	<.001	3	8
LSCC	UTP4 →	+0.368	+0.846	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,009 associations by consensus.

CAD vs WDR75 — LSCC

Explore this scatter interactively →