CAD

Across TCGA patient cohorts, CAD protein abundance is significantly associated with the RNA expression of many other genes, with 18,664 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CAD-associated genes across cancer lineages are SLC5A6, CENPA, and CPSF3. Each is linked with CAD in more than 8 cancer types. Because this analysis shows association rather than direction, both CAD-to-partner and partner-to-CAD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAD versus SLC5A6 in BRCA, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAD→partner) and Y-score (partner→CAD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SLC5A6 →	+1.016	+0.229	<.001	<.001	3	9
LUAD	CENPA →	+1.259	+0.298	<.001	<.001	3	8
HNSC	CPSF3 →	+0.646	+0.321	<.001	<.001	3	8
OV	KHK →	+0.721	+0.388	<.001	<.001	3	8
HNSC	WDR43 →	+0.860	+0.357	.001	<.001	3	8
HNSC	GPN1 →	+0.640	+0.320	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,664 associations by consensus.

CAD vs SLC5A6 — BRCA

Explore this scatter interactively →