CACNG4

Across TCGA cell cohorts, CACNG4 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CACNG4-associated genes across cancer lineages are GNGT1, IFNL2, and ANGPTL5. Each is linked with CACNG4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CACNG4-to-partner and partner-to-CACNG4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GNGT1 grouped by CACNG4-low versus CACNG4-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNG4→partner) and Y-score (partner→CACNG4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GNGT1 →	+0.050	+4.551	.002	.004	3	1
BLOOD_Leukemia	IFNL2 →	+0.034	+5.060	.009	.001	3	1
BLOOD_Leukemia	ANGPTL5 →	+0.022	+4.276	.007	.007	3	1
BLOOD_Leukemia	KRTAP12-3 →	+0.092	+4.539	<.001	.007	3	1
LARGE_INTESTINE	TIFAB →	+0.006	+4.977	<.001	.007	3	1
BLOOD_Leukemia	IP6K3 →	+0.028	+4.234	.001	.007	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

GNGT1 by CACNG4 expression — BLOOD_Leukemia

Explore this box plot interactively →