CACNG2

Across TCGA patient cohorts, CACNG2 mutation is significantly associated with the RNA expression of many other genes, with 607 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CACNG2-associated genes across cancer lineages are DCANP1, MIR4449, and RNU6-927P. Each is linked with CACNG2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CACNG2-to-partner and partner-to-CACNG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DCANP1 grouped by CACNG2-low versus CACNG2-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNG2→partner) and Y-score (partner→CACNG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	DCANP1 →	+0.023	+4.480	<.001	.005	3	3
UCEC	MIR4449 →	+0.473	+1.654	<.001	.005	3	3
CESC	RNU6-927P →	+0.384	+5.103	<.001	.008	3	2
CESC	RNA5SP481 →	+0.395	+5.669	<.001	.003	3	2
CESC	OPCML-IT1 →	+0.196	+5.201	<.001	.007	3	2
UCEC	LSM10 →	+0.322	+2.272	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 607 associations by consensus.

DCANP1 by CACNG2 expression — HNSC

Explore this box plot interactively →