CACNB4

Across TCGA patient cohorts, CACNB4 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,827 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CACNB4-associated proteins across cancer lineages are ITSN1, DDX21_S121, and EPB41L2. Each is linked with CACNB4 in more than 5 cancer types. Because this analysis shows association rather than direction, both CACNB4-to-partner and partner-to-CACNB4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CACNB4 versus ITSN1 in BRCA, with a Pearson correlation of 0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNB4→partner) and Y-score (partner→CACNB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ITSN1 →	+0.331	+0.370	<.001	.001	3	6
LUAD	DDX21_S121 →	-0.696	-0.502	<.001	.002	3	5
PDAC	EPB41L2 →	+0.328	+0.219	<.001	.005	3	5
BRCA	LUM →	+0.967	+0.350	<.001	<.001	3	5
PDAC	TOM1L2 →	+0.289	+0.255	<.001	<.001	3	4
BRCA	POLR1B →	-0.461	-0.419	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,827 associations by consensus.

CACNB4 vs ITSN1 — BRCA

Explore this scatter interactively →