CACNB4

Across TCGA cell cohorts, CACNB4 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CACNB4-associated genes across cancer lineages are CCDC185, C9orf92, and PRAMEF2. Each is linked with CACNB4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CACNB4-to-partner and partner-to-CACNB4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC185 grouped by CACNB4-low versus CACNB4-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNB4→partner) and Y-score (partner→CACNB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	CCDC185 →	+0.048	+4.635	<.001	.003	3	1
SOFT_TISSUE	C9orf92 →	+0.144	+4.369	<.001	.008	3	1
LUNG_NSCLC_LUAD	PRAMEF2 →	+0.008	+3.734	.001	.006	3	1
LUNG_NSCLC_LUAD	USP29 →	+0.009	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	ASB17 →	+0.029	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR51F2 →	+0.019	+4.078	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

CCDC185 by CACNB4 expression — SOFT_TISSUE

Explore this box plot interactively →