CACNB3

Across TCGA patient cohorts, CACNB3 mutation is significantly associated with the RNA expression of many other genes, with 2,206 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CACNB3-associated genes across cancer lineages are PSAT1P4, ADRA2C, and RPL23AP82. Each is linked with CACNB3 in more than 2 cancer types. Because this analysis shows association rather than direction, both CACNB3-to-partner and partner-to-CACNB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PSAT1P4 grouped by CACNB3-low versus CACNB3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNB3→partner) and Y-score (partner→CACNB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PSAT1P4 →	+0.178	+2.463	.001	.009	3	3
UCEC	ADRA2C →	-1.072	-2.906	<.001	.001	3	2
UCEC	RPL23AP82 →	+0.427	+2.273	<.001	<.001	3	2
UCEC	SNAI3 →	+0.326	+2.743	.009	.002	3	2
UCEC	MAPK12 →	+0.723	+2.343	<.001	.003	3	2
UCEC	IGLV1-36 →	+1.463	+2.617	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,206 associations by consensus.

PSAT1P4 by CACNB3 expression — COAD

Explore this box plot interactively →