CACNB1

Across TCGA patient cohorts, CACNB1 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,354 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CACNB1-associated proteins across cancer lineages are PMM2, MAP1B_S1016, and PIP4K2B. Each is linked with CACNB1 in more than 5 cancer types. Because this analysis shows association rather than direction, both CACNB1-to-partner and partner-to-CACNB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CACNB1 versus PMM2 in BRCA, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNB1→partner) and Y-score (partner→CACNB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PMM2 →	-0.382	-0.745	<.001	<.001	3	6
OV	MAP1B_S1016 →	+1.353	+0.719	.001	<.001	3	4
GBM	PIP4K2B →	+0.448	+0.932	<.001	<.001	3	4
GBM	TBC1D24 →	+0.545	+0.723	<.001	<.001	3	4
HNSC	SP4_S46 →	+0.728	+0.880	<.001	<.001	3	4
LSCC	SLC9A1_S796 →	-0.586	-0.444	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,354 associations by consensus.

CACNB1 vs PMM2 — BRCA

Explore this scatter interactively →