CACNB1

Across TCGA patient cohorts, CACNB1 mutation is significantly associated with the RNA expression of many other genes, with 1,369 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CACNB1-associated genes across cancer lineages are RNU6-1317P, KMT5AP1, and RNU6-679P. Each is linked with CACNB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CACNB1-to-partner and partner-to-CACNB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1317P grouped by CACNB1-low versus CACNB1-high in THCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNB1→partner) and Y-score (partner→CACNB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	RNU6-1317P →	+0.244	+7.962	<.001	.007	3	2
UCEC	KMT5AP1 →	+0.192	+1.418	<.001	.002	3	2
SKCM	RNU6-679P →	+0.173	+4.634	<.001	.003	3	2
SARC	SPATA31D2P →	+0.048	+5.477	<.001	.004	3	2
HNSC	MIR3158-1 →	+0.638	+5.578	<.001	.004	3	2
CESC	RN7SL250P →	+1.297	+4.653	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,369 associations by consensus.

RNU6-1317P by CACNB1 expression — THCA

Explore this box plot interactively →