CACNA2D3-AS1

Across TCGA pan-cancer cohorts, CACNA2D3-AS1 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated CACNA2D3-AS1 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher CACNA2D3-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated CACNA2D3-AS1 expression acts as an unfavorable survival marker, although some lineages such as LUSC and HNSC show a favorable association.

LUSC, KIRC, and UCEC are the cancer types where CACNA2D3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Median	All	0.741	0.610	<.001	78	view →
KIRC	DFS	Tertile	All	0.464	0.719	.001	47	view →
UCEC	DFS	Tertile	All	0.849	0.913	.001	44	view →
READ	DFS	Tertile	IV	0.226	0.682	<.001	42	view →
HNSC	DFS	Quartile	IV	0.859	0.622	.001	32	view →
CESC	DFS	Quartile	All	0.849	0.691	.006	30	view →
LUAD	DFS	Median	IV	0.327	0.761	.001	18	view →
MESO	OS	Quartile	II,III,IV	0.260	0.420	.026	13	view →
KIRP	OS	Median	All	0.977	0.890	.001	11	view →
SKCM	DFS	Tertile	IV	0.016	0.541	.008	9	view →
BLCA	DFS	Quartile	III,IV	0.446	0.590	.012	9	view →
DLBC	DFS	Tertile	All	0.559	0.935	.020	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

CACNA2D3-AS1–LUSC (OS)

Open the LUSC breakdown →