CACNA2D3-AS1

Across TCGA pan-cancer cohorts, CACNA2D3-AS1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of CACNA2D3-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CACNA2D3-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types CACNA2D3-AS1 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, KICH, and LUSC are the cancer types where CACNA2D3-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CACNA2D3-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	−0.025	.001	7	view →
KICH	Male	All	−0.039	.001	6	view →
LUSC	All	All	+0.076	.004	4	view →
THCA	All	All	−0.043	<.001	4	view →
HNSC	Female	IV	−0.071	.023	2	view →
UCEC	All	All	+0.030	.044	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

CACNA2D3-AS1–KIRC

Open the KIRC breakdown →