CACNA2D1

Across TCGA patient cohorts, CACNA2D1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,403 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CACNA2D1-associated proteins across cancer lineages are CCDC80, DAB2, and PRKG1. Each is linked with CACNA2D1 in more than 6 cancer types. Because this analysis shows association rather than direction, both CACNA2D1-to-partner and partner-to-CACNA2D1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CACNA2D1 versus CCDC80 in COAD, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNA2D1→partner) and Y-score (partner→CACNA2D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CCDC80 →	+0.807	+0.684	<.001	<.001	3	7
GBM	DAB2 →	+0.524	+1.291	.001	<.001	3	7
UCEC	PRKG1 →	+0.770	+0.777	<.001	<.001	3	7
COAD	ASPN →	+1.018	+0.633	<.001	<.001	3	6
UCEC	SEPTIN11 →	+0.393	+0.805	<.001	<.001	3	6
BRCA	SERPINF1 →	+0.845	+1.054	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,403 associations by consensus.

CACNA2D1 vs CCDC80 — COAD

Explore this scatter interactively →