CACNA1F

Across TCGA patient cohorts, CACNA1F mutation is significantly associated with the total protein of many other genes, with 68 significant associations in total. COAD shows the largest number of these associations.

The most reproducible CACNA1F-associated genes across cancer lineages are ATM, AMPK_pT172, and Rad50. Each is linked with CACNA1F in more than 3 cancer types. Because this analysis shows association rather than direction, both CACNA1F-to-partner and partner-to-CACNA1F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by CACNA1F-low versus CACNA1F-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNA1F→partner) and Y-score (partner→CACNA1F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ATM →	-0.532	-3.000	.001	.037	3	4
BRCA	AMPK_pT172 →	-0.432	-2.459	.004	.021	3	3
UCEC	Rad50 →	-0.143	-1.285	.016	.001	3	3
COAD	4E-BP1_pT70 →	+0.101	+1.700	.014	.040	3	3
UCEC	eIF4E →	+0.177	+1.550	<.001	<.001	3	2
UCEC	Notch1 →	+0.097	+1.039	.005	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 68 associations by consensus.

ATM by CACNA1F expression — BRCA

Explore this box plot interactively →