CACNA1F

Across TCGA pan-cancer cohorts, CACNA1F RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated CACNA1F data layer compared with 7 for mutation status.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher CACNA1F RNA is associated with better overall survival. In most high-consensus cancer types, elevated CACNA1F expression acts as an unfavorable survival marker, although some lineages such as BRCA and HNSC show a favorable association.

BRCA, LUSC, and HNSC are the cancer types where CACNA1F RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	III,IV	0.957	0.847	.001	55	view →
LUSC	OS	Median	III,IV	0.205	0.765	.006	39	view →
HNSC	DFS	Median	IV	0.727	0.556	<.001	35	view →
BLCA	OS	Tertile	All	0.796	0.685	.009	33	view →
LIHC	OS	Median	All	0.706	0.850	.001	30	view →
COAD	OS	Quartile	All	0.724	0.876	.005	25	view →
SARC	OS	Median	All	0.931	0.781	<.001	24	view →
CESC	OS	Quartile	IV	0.879	0.368	.014	20	view →
LAML	DFS	Median	All	0.441	0.698	.008	18	view →
LGG	DFS	Quartile	All	0.379	0.504	.020	12	view →
READ	DFS	Median	IV	0.379	0.772	.006	12	view →
KIRC	DFS	Quartile	All	0.525	0.687	.006	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

CACNA1F–BRCA (OS)

Open the BRCA breakdown →