CACNA1F

Across TCGA cell cohorts, CACNA1F mutation is significantly associated with the RNA expression of many other genes, with 587 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CACNA1F-associated genes across cancer lineages are CYP3A4, HACE1, and VSX2. Each is linked with CACNA1F in more than 2 cancer types. Because this analysis shows association rather than direction, both CACNA1F-to-partner and partner-to-CACNA1F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CYP3A4 grouped by CACNA1F-low versus CACNA1F-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNA1F→partner) and Y-score (partner→CACNA1F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CYP3A4 →	+0.178	+3.966	<.001	<.001	3	3
LARGE_INTESTINE	HACE1 →	+0.817	+2.265	<.001	.001	3	3
BLOOD_Leukemia	VSX2 →	+0.019	+3.258	.007	.007	3	2
BLOOD_Leukemia	JAKMIP1 →	+2.739	+3.266	<.001	.007	3	2
BLOOD_Leukemia	KSR2 →	+0.417	+3.061	<.001	.003	3	2
BLOOD_Leukemia	TMEM132C →	+0.620	+2.966	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 587 associations by consensus.

CYP3A4 by CACNA1F expression — BLOOD_Leukemia

Explore this box plot interactively →