Across TCGA patient cohorts, CACNA1E protein abundance is significantly associated with the RNA expression of many other genes, with 2,887 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CACNA1E-associated genes across cancer lineages are SNRPD3, PRODH, and LGALS1. Each is linked with CACNA1E in more than 1 cancer types. Because this analysis shows association rather than direction, both CACNA1E-to-partner and partner-to-CACNA1E results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNA1E→partner) and Y-score (partner→CACNA1E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SNRPD3 →	+0.362	+0.453	.006	.001	3	1
GBM	PRODH →	+0.772	+0.432	<.001	<.001	3	1
GBM	LGALS1 →	-0.541	-0.340	.005	.005	3	1
GBM	SOX10 →	+1.088	+0.423	.001	<.001	3	1
GBM	SLC16A8 →	+0.532	+0.344	.001	.001	3	1
GBM	SEPTIN3 →	+1.436	+0.568	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,887 associations by consensus.

Exploration

CACNA1E survival (RNA) · tumor vs normal (RNA) · all CACNA1E data types