CACNA1E

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CACNA1E RNA expression is significantly associated with the go_rna of many other GO terms, with 2,235 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CACNA1E-associated GO terms across cancer lineages are Nuclear receptor-mediated steroid hormone signaling pathway, Steroid hormone receptor signaling pathway, and Positive regulation of intracellular transport. Each is linked with CACNA1E in more than 5 cancer types. Because this analysis shows association rather than direction, both CACNA1E-to-partner and partner-to-CACNA1E results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNA1E→partner) and Y-score (partner→CACNA1E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONENuclear receptor-mediated steroid hormone signaling pathway →+0.062+0.037.003.00636
BONESteroid hormone receptor signaling pathway →+0.062+0.037.003.00636
BONEPositive regulation of intracellular transport →+0.071+0.054<.001.00635
LUNG_SCLCRegulation of proteasomal protein catabolic process →+0.065+1.630<.001<.00135
PANCREASGolgi vesicle transport →+0.041+0.028.001<.00135
LUNG_SCLCSkeletal muscle satellite cell activation →+1.089+1.238<.001.00435
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,235 associations by consensus.

Exploration