Across TCGA cell cohorts, CACNA1E mutation is significantly associated with the RNA expression of many other genes, with 1,274 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CACNA1E-associated genes across cancer lineages are DYM, SGCB, and MPV17L2. Each is linked with CACNA1E in more than 3 cancer types. Because this analysis shows association rather than direction, both CACNA1E-to-partner and partner-to-CACNA1E results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNA1E→partner) and Y-score (partner→CACNA1E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	DYM →	+0.606	+1.628	.001	.002	3	3
LARGE_INTESTINE	SGCB →	+0.864	+2.000	<.001	<.001	3	3
LARGE_INTESTINE	MPV17L2 →	+0.347	+2.087	.004	.001	3	3
BLOOD_Leukemia	TRIM62 →	+0.710	+3.489	<.001	.001	3	3
BLOOD_Lymphoma	MUC21 →	+0.078	+3.874	.006	.001	3	2
LARGE_INTESTINE	GCAT →	+1.162	+2.000	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,274 associations by consensus.

Exploration

CACNA1E survival (RNA) · tumor vs normal (RNA) · all CACNA1E data types