CACNA1B

Across TCGA cell cohorts, CACNA1B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,841 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CACNA1B-associated GO terms across cancer lineages are Regulation of nucleobase-containing compound transport, Positive regulation of synaptic vesicle exocytosis, and 5S class rRNA transcription by RNA polymerase III. Each is linked with CACNA1B in more than 8 cancer types. Because this analysis shows association rather than direction, both CACNA1B-to-partner and partner-to-CACNA1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nucleobase-containing compound transport grouped by CACNA1B-low versus CACNA1B-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNA1B→partner) and Y-score (partner→CACNA1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of nucleobase-containing compound transport →	+0.119	+0.692	<.001	.002	3	9
OESOPHAGUS	Positive regulation of synaptic vesicle exocytosis →	-1.185	-0.688	<.001	<.001	3	9
BONE	5S class rRNA transcription by RNA polymerase III →	+0.133	+1.133	<.001	<.001	3	9
OVARY	Positive regulation of calcium ion-dependent exocytosis of neurotransmitter →	-1.054	-0.698	<.001	<.001	3	8
BONE	tRNA transcription by RNA polymerase III →	+0.119	+1.106	<.001	<.001	3	8
OESOPHAGUS	Positive regulation of translation →	+0.091	+0.792	.001	.004	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,841 associations by consensus.

Regulation of nucleobase-containing compound transport by CACNA1B expression — OVARY

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