CABYR

Across TCGA pan-cancer cohorts, CABYR Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated CABYR data layer compared with 22 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher CABYR Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated CABYR expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

CESC, HNSC, and LUSC are the cancer types where CABYR Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Median	All	0.053	0.823	<.001	42	view →
HNSC	OS	Median	II,III,IV	0.021	0.712	<.001	33	view →
LUSC	DFS	Median	II,III,IV	0.079	0.750	<.001	24	view →
SARC	DFS	Median	All	0.098	0.611	.006	6	view →
UCEC	DFS	Median	All	0.947	0.629	.044	4	view →
ACC	DFS	Median	All	0.195	0.748	.003	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

CABYR–CESC (DFS)

Open the CESC breakdown →