CABS1

Across TCGA cell cohorts, CABS1 RNA expression is significantly associated with the mutation status of many other genes, with 87 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CABS1-associated genes across cancer lineages are PRRG2, ADGRE2, and RHOT1. Each is linked with CABS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CABS1-to-partner and partner-to-CABS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRRG2 grouped by CABS1-low versus CABS1-high in CNS.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CABS1→partner) and Y-score (partner→CABS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	PRRG2 →	+3.302	+0.537	.003	<.001	3	2
SKIN	ADGRE2 →	+4.415	+0.034	.007	<.001	3	2
LUNG_NSCLC_LUSC	RHOT1 →	+4.643	+0.100	.008	<.001	3	1
LUNG_NSCLC_LUSC	TEX2 →	+4.643	+0.100	.008	<.001	3	1
LUNG_NSCLC_LUSC	TRIM42 →	+4.643	+0.100	.008	<.001	3	1
LUNG_NSCLC_LUSC	XRRA1 →	+4.643	+0.100	.008	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 87 associations by consensus.

PRRG2 by CABS1 expression — CNS

Explore this box plot interactively →