CABP2

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CABP2 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CABP2 data layer compared with 18 for mass-spec protein.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher CABP2 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CABP2 expression acts as an unfavorable survival marker.

CESC, STAD, and UCEC are the cancer types where CABP2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CESCOSMedianIII,IV0.0680.756<.00112view →
STADOSMedianII,III,IV0.1830.659.0376view →
UCECOSMedianIV0.2310.592.0366view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CABP2–CESC (OS)

Kaplan–Meier survival curve for CABP2 mutant vs wild-type samples in CESC.

Open the CESC breakdown →

Exploration