Across TCGA pan-cancer cohorts, CABP2 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of CABP2’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where CABP2 RNA is repressed in tumor relative to normal tissue. In most cancer types CABP2 is over-expressed in tumor, although a few such as COAD and KICH show the opposite, repressed pattern.
COAD, KICH, and BRCA are the cancer types where CABP2 tumor–normal differential expression is most reproducible.