CABP2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CABP2 mutation is significantly associated with the RNA expression of many other genes, with 691 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CABP2-associated genes across cancer lineages are SNORD62A, MTATP6P4, and DLAT. Each is linked with CABP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CABP2-to-partner and partner-to-CABP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD62A grouped by CABP2-low versus CABP2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CABP2→partner) and Y-score (partner→CABP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMSNORD62A →+0.612+3.654.001.00332
LUADMTATP6P4 →+0.063+6.739<.001<.00132
UCECDLAT →+0.655+2.700.003.00632
UCECSLC22A17 →-1.267-3.807<.001<.00132
UCECUTP4 →+0.630+2.700<.001.00632
UCECSNORD15A →+0.489+2.555<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 691 associations by consensus.

SNORD62A by CABP2 expression — SKCM

Box plot of SNORD62A in CABP2-low vs CABP2-high samples in SKCM.

Explore this box plot interactively →

Exploration