CABP2

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CABP2 mutation is significantly associated with the immune_cell of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CABP2-associated genes across cancer lineages are GMP, mv Endothelial cells, and Endothelial cells. Each is linked with CABP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CABP2-to-partner and partner-to-CABP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMP grouped by CABP2-low versus CABP2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CABP2→partner) and Y-score (partner→CABP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMGMP →+0.052+2.543<.001.01032
UCECmv Endothelial cells →-0.024-1.989.023.03232
UCECEndothelial cells →-0.037-2.657.029.00631
UCECEpithelial cells →-0.089-2.000.005.03231
UCECMesangial cells →-0.053-3.258.002.01031
UCECMyocytes →+0.042+3.076.004.01631
Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

GMP by CABP2 expression — SKCM

Box plot of GMP in CABP2-low vs CABP2-high samples in SKCM.

Explore this box plot interactively →

Exploration