CABIN1

Across TCGA cell cohorts, CABIN1 mutation is significantly associated with the RNA expression of many other genes, with 941 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CABIN1-associated genes across cancer lineages are CAPZA1, METTL21A, and ME2. Each is linked with CABIN1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CABIN1-to-partner and partner-to-CABIN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CAPZA1 grouped by CABIN1-low versus CABIN1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CABIN1→partner) and Y-score (partner→CABIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CAPZA1 →	+0.430	+3.459	<.001	.002	3	3
BLOOD_Leukemia	METTL21A →	+0.475	+3.285	.001	.004	3	3
LARGE_INTESTINE	ME2 →	+1.081	+3.321	<.001	.003	3	3
LARGE_INTESTINE	PPA2 →	+0.509	+2.064	.003	.004	3	3
LARGE_INTESTINE	HPF1 →	+0.705	+2.459	<.001	.005	3	3
LARGE_INTESTINE	TXNL1 →	+0.708	+3.459	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 941 associations by consensus.

CAPZA1 by CABIN1 expression — BLOOD_Leukemia

Explore this box plot interactively →