CABIN1

Across TCGA pan-cancer cohorts, CABIN1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of CABIN1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where CABIN1 RNA is repressed in tumor relative to normal tissue. In most cancer types CABIN1 is over-expressed in tumor, although a few such as THCA and LUAD show the opposite, repressed pattern.

THCA, HNSC, and LIHC are the cancer types where CABIN1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CABIN1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	III,IV	−1.271	<.001	11	view →
HNSC	Male	All	+0.770	<.001	10	view →
LIHC	Female	II,III,IV	+1.663	<.001	9	view →
CHOL	Male	All	+2.518	<.001	5	view →
STAD	All	All	+0.699	<.001	5	view →
BRCA	All	All	+0.235	.004	4	view →
COAD	All	All	+0.198	.036	3	view →
READ	All	III,IV	+0.545	.049	2	view →
KIRP	All	IV	+0.434	.041	2	view →
LUAD	Male	All	−0.363	.020	2	view →
ESCA	All	All	+0.782	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

CABIN1–THCA

Open the THCA breakdown →