CAB39L

Across TCGA pan-cancer cohorts, CAB39L Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CAB39L data layer compared with 21 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in thymoma (THYM), where higher CAB39L Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CAB39L expression acts as an unfavorable survival marker.

THYM, BLCA, and SKCM are the cancer types where CAB39L Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Median	III,IV	0.103	0.944	<.001	42	view →
BLCA	DFS	Median	All	0.083	0.626	<.001	24	view →
SKCM	DFS	Median	All	0.072	0.733	<.001	15	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CAB39L–THYM (OS)

Open the THYM breakdown →